Large payout, including progressive jackpot rewards, have no effect on the slot machine PRNG algorithm or hits. If a lucky player wins the maximum reward on a slot machine, they have the same chances of winning the maximum jackpot on another slot cabinet or digital game. The odds of hitting a slot machine are the same regardless of how much money was spent or earned.
Large payout do not effect when slot hits
Large payouts do not effect the PRNG directly, but they can influence slot machine hit indirectly. Certain casino software allows operators to tweak the RNG of their slot machines. That is a fair response when a machine is losing money and not making money. Low slot machine hits are possible even among titles with huge rewards. However, this only happens on a few casino platforms, and operators risk losing paying clients if their slots are revealed to be rigged to pay out less.
Because a slot machine employs a PRNG algorithm to select which symbols will fall on the reels, there is no way of knowing when it will hit. However, the RTP and volatility of a slot machine can give you a good idea of how frequently it hits. Conclusion is that large payout does not have impact on chances when slot hits.